"So long as our relationship is defined by our differences, we will empower those who sow hatred rather than peace, those who promote conflict rather than the cooperation that can help all of our people achieve justice and prosperity. And this cycle of suspicion and discord must end."

"America is not-- and never will be-- at war with Islam. We will, however, relentlessly confront violence extremists who pose a grave threat to our security-- because we reject the same thing that people of all faiths reject: the killing of innocent men, women and children."

“One year ago, I took office amid two wars, an economy rocked by severe recession, a financial system on the verge of collapse, and a government deeply in debt. Experts from across the political spectrum warned that if we did not act, we might face a second depression. So we acted -– immediately and aggressively. And one year later, the worst of the storm has passed.”

“Here's what I ask Congress, though: Don't walk away from reform. Not now. Not when we are so close. Let us find a way to come together and finish the job for the American people. (Applause.) Let's get it done. Let's get it done.”

“Rather than fight the same tired battles that have dominated Washington for decades, it's time to try something new. Let's invest in our people without leaving them a mountain of debt. Let's meet our responsibility to the citizens who sent us here. Let's try common sense. (Laughter.) A novel concept.”

“I campaigned on the promise of change –- change we can believe in, the slogan went. And right now, I know there are many Americans who aren't sure if they still believe we can change –- or that I can deliver it. But remember this –- I never suggested that change would be easy, or that I could do it alone. Democracy in a nation of 300 million people can be noisy and messy and complicated. And when you try to do big things and make big changes, it stirs passions and controversy. That's just how it is.”

“The spirit that has sustained this nation for more than two centuries lives on in you, its people. We have finished a difficult year. We have come through a difficult decade. But a new year has come. A new decade stretches before us. We don't quit. I don't quit. (Applause.) Let's seize this moment -- to start anew, to carry the dream forward, and to strengthen our union once more.”

If you're willing to speak out strongly on behalf of the things you care about and what you see each and every day as you're serving patients all across the country, I'm confident we are going to get health reform passed this year.

“When you ask me that question I am going to revert to my ethnic heritage and answer your question with a question. On what planet do you spend most of your time? Do you want me to answer the question? Yes. As you stand there with a picture of the President defaced to look like Hitler, and compare the effort to increase health care to the Nazis, my answer to you is as I said before, it is a tribute to the First Amendment that this kind of vile, contemptible nonsense is so freely propagated. Ma’am, trying to have a conversation with you would be like trying to argue with a dining room table. I have no interest in doing it.”

“Wait. You want me to tell you what my husband thinks? My husband is not the Secretary of State. I am. So you ask my opinion, I will tell you my opinion. I’m not going to be channeling my husband.”